Charles Green Bush, a contemporary of Homer Davenport’s, was born in Boston in 1842. He began contributing political cartoons to Harper’s Weekly in the 1870’s and in 1875 studied art in Paris with Léon Bonnat, the portrait painter before returning to New York in 1879 to continue at the Weekly. Both Harper's Weekly and Harper's Magazine were pioneers in the early use of sequential art in America, most importantly in the work of A. B. Frost.
Bush was not known for his comic strip work but in 1890 he drew a series of comics for Harper’s Weekly that show the influence of A. B. Frost, and, in the case of the animated ‘baseball’ strip, probably Eadweard Muybridge, whose photographic studies in human and animal locomotion (1878) had a seminal influence on both the cinema and the comic strip.
Charles Green Bush (1842-1909) illustrated Canadian writer James De Mille's novel The Lady of the Ice (1870), Adeline Dutton Train's Faith Gartney's Girlhood, (1891), and Rhoda Thornton's Girlhood by Mary E. Pratt.(1874). In his book The Political Cartoon, Charles Press argues that the first use of Uncle Sam in a cartoon was by Charles Green Bush on February 6, 1869 in Harper's Weekly, as Frank Weitenkampf showed in "Uncle Sam Through The Years : A Cartoon Record, Annotated List and Introduction," an unpublished manuscript in the New York Public Library, 1949, 24 pg. By 1900 Press states Bush was known as the "dean of American Political cartooning."